ˈtʃɛ koː
checo
gon ˈsă les
gonzales
TL;DR:
About:
I’m a PhD Candidate in Biomedical Informatics at Stanford University and on a leave of absence from the MD program at the University of New Mexico School of Medicine. I completed an interdisciplinary BA in Mathematics, Statistics, and Physical, Natural & Social Sciences with minors in Navajo Language & Linguistics and Chicana & Chicano Studies in 2015. I was a Visiting Student in the Dept. of Economics at Harvard 2015-2017. In 2018, I was a fellow at the Washington University School of Medicine Mallinckrodt Institute of Radiology.
Email me: checo [dot] gonzales [at] protonmail [dot] com
Research:
Variation in human sex physiology is essential to consider in all biomedical research, but there are no variables or methods to construct variables that faithfully represent sex physiology. Most researchers use assigned sex at birth (ASAB), which is a binary, legal record of the gross morphology of a neonate’s genitalia and it is assigned despite any differences of sexual development (DSD) that alter morphology or physiology. ASAB does not capture inherent variation in the gene regulatory networks, acquired pathology, environmental exposures, and medical interventions that alter sex physiology over the course of trans*, cisgender, and people with DSD’s lives alike.
I study machine learning methods to construct a representation of human sex physiology that can be used in place of ASAB in clinical informatics research. This variable is constructed using only objective, observable, routine laboratory tests and biomarkers present in existing electronic health records. In particular, I research auto-encoder algorithms in multi-task settings, probabilistic graph models, variational inference, and meta-learning networks.
Previously, I worked on CV methods to isolate and featurize autofluorescent signals in megapixel resolution, multiplexed immunofluorescence experiments, multi-class segmentation of intercranial tumors, characterization of provider-patient emails with NLP methods , and disparity in provision of health services and insurance.
Publications:
JA Lossio-Ventura, S Gonzales, J Morzan, H Alatrista-Salas, T Hernandez-Boussard, & J Bian. Evaluation of clustering and topic modeling methods over health-related tweets and emails. Artificial Intelligence in Medicine. 2021
S Gonzales & BD Sommers. Intra-Ethnic Coverage Disparities among Latinos and the Effects of Health Reform. Health ServRes. 2018.
S Gonzales, M Mullen, L Skolarus, D Thibault, U Udoeyo, & A Willis. Progressive Rural-Urban Disparity in Acute Stroke Care. Neurology, 2017.